Cleavage bodies are nuclear bodies which contain factors that are necessary for RNA transcription and/or processing. Cleavage bodies often colocalize with other nuclear bodies, such as DDX1 body and Cajal body (16371507, 8654386).
Formation, Composition & dynamics (Assembly and disassembly)
Relation to human diseases
Proteome
References
Li L, Roy K, Katyal S, Sun X, Bléoo S, Godbout R. Dynamic nature of cleavage bodies and their spatial relationship to DDX1 bodies, Cajal bodies, and gems. Mol Biol Cell. 2006 Mar;17(3):1126-40. doi: 10.1091/mbc.e05-08-0768. Epub 2005 Dec 21. PMID: 16371507; PMCID: PMC1382303.
Schul W, Groenhout B, Koberna K, Takagaki Y, Jenny A, Manders EM, Raska I, van Driel R, de Jong L. The RNA 3' cleavage factors CstF 64 kDa and CPSF 100 kDa are concentrated in nuclear domains closely associated with coiled bodies and newly synthesized RNA. EMBO J. 1996 Jun 3;15(11):2883-92. PMID: 8654386; PMCID: PMC450226.