Phase separated cytoplasmic proteins forming aggregates in the cytoplasm. A hallmark of neurodegenerative diseases is the accumulation of cytoplasmic protein aggregates in neurons (further detail: 30406848).
Formation, Composition & dynamics (Assembly and disassembly)
Relation to human diseases
Proteome
References
Dobra I, Pankivskyi S, Samsonova A, Pastre D, Hamon L. Relation Between Stress Granules and Cytoplasmic Protein Aggregates Linked to Neurodegenerative Diseases. Curr Neurol Neurosci Rep. 2018 Nov 8;18(12):107. doi: 10.1007/s11910-018-0914-7. PMID: 30406848.