The Histone Locus Body (HLB) is a nucleus subdomain characterized by the concentration of components required for histone gene transcription and pre-mRNA processing. Histone mRNAs production takes place in HLBs (28059623).
Duronio RJ, Marzluff WF. Coordinating cell cycle-regulated histone gene expression through assembly and function of the Histone Locus Body. RNA Biol. 2017 Jun 3;14(6):726-738. doi: 10.1080/15476286.2016.1265198. Epub 2017 Jan 6. PMID: 28059623; PMCID: PMC5519241.