Neuronal RNP granules are nonmembrane bound macromolecular condensates that concentrate certain sets of mRNAs and regulatory proteins, allowing them to travel longer distances to axons or dendrites. RNP granules in neurons have a dual role in regulating the translation of linked mRNAs: at rest, they impede mRNA translation, but once activated, they fuel local protein synthesis (further detail: 31206920).
Formicola N, Vijayakumar J, Besse F. Neuronal ribonucleoprotein granules: Dynamic sensors of localized signals. Traffic. 2019 Sep;20(9):639-649. doi: 10.1111/tra.12672. Epub 2019 Jul 29. PMID: 31206920.