Insulator bodies are specific nuclear speckles that function as regulatory elements in modulating enhancer-promoter interactions. Insulator bodies are enriched in chromatin insulator proteins (22375064).
Golovnin A, Volkov I, Georgiev P. SUMO conjugation is required for the assembly of Drosophila Su(Hw) and Mod(mdg4) into insulator bodies that facilitate insulator complex formation. J Cell Sci. 2012 Apr 15;125(Pt 8):2064-74. doi: 10.1242/jcs.100172. Epub 2012 Feb 28. PMID: 22375064.