Proteins from the Polycomb Group (PcG) are clustered in nuclear foci known as PcG bodies. PcG proteins regulate the expression of a wide range of genes by silencing them (reviewed in 22178420, 21680045).
Formation, Composition & dynamics (Assembly and disassembly)
Relation to human diseases
Proteome
References
Pirrotta V, Li HB. A view of nuclear Polycomb bodies. Curr Opin Genet Dev. 2012 Apr;22(2):101-9. doi: 10.1016/j.gde.2011.11.004. Epub 2011 Dec 16. PMID: 22178420; PMCID: PMC3329586.
Mao YS, Zhang B, Spector DL. Biogenesis and function of nuclear bodies. Trends Genet. 2011 Aug;27(8):295-306. doi: 10.1016/j.tig.2011.05.006. Epub 2011 Jun 15. PMID: 21680045; PMCID: PMC3144265.