DDX1 body is a type of nuclear bodies. DDX1 bodies contain the protein DEAD box DDX1 protein, which is a potential RNA unwinding protein linked to RNA processing and transport. Cleavage bodies and DDX1 bodies are frequently found colocalizing in the nucleus (16371507, 11598190).
Formation, Composition & dynamics (Assembly and disassembly)
Relation to human diseases
Proteome
References
Li L, Roy K, Katyal S, Sun X, Bléoo S, Godbout R. Dynamic nature of cleavage bodies and their spatial relationship to DDX1 bodies, Cajal bodies, and gems. Mol Biol Cell. 2006 Mar;17(3):1126-40. doi: 10.1091/mbc.e05-08-0768. Epub 2005 Dec 21. PMID: 16371507; PMCID: PMC1382303.
Bléoo S, Sun X, Hendzel MJ, Rowe JM, Packer M, Godbout R. Association of human DEAD box protein DDX1 with a cleavage stimulation factor involved in 3'-end processing of pre-MRNA. Mol Biol Cell. 2001 Oct;12(10):3046-59. doi: 10.1091/mbc.12.10.3046. PMID: 11598190; PMCID: PMC60154.